Diagnosis of Protein-Energy Deficiency: The Role of Total Protein and Transferrin in the Blood

Authors

  • Ashurova G. Z.
  • Satvaldieva E. A. Tashkent Paediatric Medical Institute Children's National Medical Center

Keywords:

PEM, role, blood system, biochemical process, diagnoses, clinical measures.

Abstract

The diagnosis of protein-energy deficiency, also known as protein-energy malnutrition (PEM), is a complex process that requires the evaluation of multiple biochemical and anthropometric parameters. Among these, total protein and transferrin in the blood play a crucial role in identifying individuals at risk of PEM. This article will discuss the significance of total protein and transferrin in the diagnosis of PEM, highlighting their physiological roles, laboratory measurements, and clinical implications.

References

Ingen leek Y. Plasma Transthyretin as a Biomarker of Sarcopenia in Elderly Subjects. Nutrients. 2019; 11:895. Doi: 10.3390/nu11040895.

Spiekerman A. Nutritional assessment (protein Nutriture) Anal. Chem. 1995; 67:429–436. Doi: 10.1021/ac00108a026.

Dellière S., Cynober L. Is transthyretin a good marker of nutritional status? Clin. Nutr. 2017; 36:364–370. Doi: 10.1016/j.clnu.2016.06.004.

Li L., Dai L., Wang X., Wang Y., Zhou L., Chen M., Wang H. Predictive value of the C-reactive protein-to-prealbumin ratio in medical ICU patients. Biomarker. Med. 2017; 11:329–337. Doi: 10.2217/bmm-2016-0266.

Harriman S., Rotich N., Hayes P., Moser M.A. The C-reactive protein-to-prealbumin ratio predicts fistula closure. Am. J. Surg. 2011; 202:175–178. Doi: 10.1016/j.amjsurg.2010.06.021.

Shen Q., Liu W., Quan H., Pan S., Li S., Zhou T., Ouyang Y., Xiao H. Prealbumin and lymphocyte-based prognostic score, a new tool for predicting long-term survival after curative resection of stage II/III gastric cancer. Br. J. Nutra. 2018; 120:1359–1369. Doi: 10.1017/S0007114518002854.

Shimura T., Shibata M., Inoue T., Owada-Ozaki Y., Yamamura T., Muto S., Hasegawa T., Shio Y., Suzuki H. Prognostic impact of serum transthyretin in patients with non-small cell lung cancer. Mol. Clin. Oncol. 2019; 10:597–604. Doi: 10.3892/mco.2019.1837.

Wang W., Wang C.-S., Ren D., Li T., Yao H.-C., Ma S.-J. Low serum prealbumin levels on admission can independently predict in-hospital adverse cardiac events in patients with acute coronary syndrome. Medicine. 2018;97: e11740. Doi: 10.1097/MD.0000000000011740.

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Published

2024-05-05

How to Cite

Ashurova G. Z., & Satvaldieva E. A. (2024). Diagnosis of Protein-Energy Deficiency: The Role of Total Protein and Transferrin in the Blood. International Journal of Scientific Trends, 3(5), 1–5. Retrieved from https://scientifictrends.org/index.php/ijst/article/view/266

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Articles